MENO COMFORT
OESTRAEDIM™
Scientifically backed formula for joint comfort and everyday movement during menopause. With 95% curcumin, broccoli extract and piperine for targeted support during this life stage.
Helps support the maintenance of flexible joints
Supports female comfort and well-being during hormonal changes
Monthly subscription
Pause anytime • Cancel from month 2
€40,50 • €45,00
€1,35/day- % 10% discount from the start, 15% from month 4, 20% from month 6
- Free jar (€15 value) per supplement
Duo Kit Meno Comfort
Jar & Refill Pouch
€50,00 • €60,00
WHY CHOOSE A SUBSCRIPTION?
Support your long-term health and save more the longer you stay. Flexible and worry-free, adjust your subscription whenever you want.
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10% discount from the first month.
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15 % from month 4, up to 20 % from month 6.
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Free pharmacy jar worth €15 per product
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Adjust your subscription whenever needed: swap or add products, change your delivery date, or pause temporarily; all through your account.
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Expert advice whenever you want: recipes, tips, and guidance.
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Automatic free home delivery.
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Early access to new products and occasional extras.
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Cancellation is possible from month 2 via your personal account.
Subscription with credit card. One-time purchase with various payment options.
Free Shipping for orders over €45
Claims
• Contributes to the maintenance of healthy joints (Curcuma longa*).
• Helps maintain natural movement comfort (Curcuma longa*).
• Supports normal nervous system function (Curcuma longa*).
• Supports nutrient absorption (Piper nigrum*).
*Health claims pending European approval.
Ingredients
RECOMMENDED USE
Amount: 1 capsule per day
When: To be taken in the morning
Duration: At least 3–6 months, in combination with a balanced diet and sufficient physical activity
Target group: Adults (18+)
Pregnancy/breastfeeding: Not recommended during pregnancy or breastfeeding, unless advised by your doctor or pharmacist
COMBINE WITH:
MENO COMFORT
OESTRAEDIM™
Duo Kit Meno Comfort
Monthly subscription
One-time purchase
Clinically supported ingredients
During menopause, estrogen levels decline, which can affect cartilage structure and metabolism. Scientific research shows that estrogen deficiency is associated with changes in joint tissues and reduced joint comfort, which is more common in women at this life stage (Yoon et al., 2018). Curcumin from Curcuma longa has been extensively studied and is traditionally used to support joint flexibility and mobility, especially with consistent use.
During menopause, hormonal fluctuations cause changes in muscle and joint function, which can contribute to stiffness and reduced movement comfort. Research in midlife women shows that declining estrogen is associated with changes in physical function and mobility (Messier et al., 2011). Targeted support that considers this life stage can help keep daily movement comfortable and maintain physical activity as part of a healthy lifestyle.
Broccoli extract contains bioactive compounds such as DIM (diindolylmethane) and sulforaphane. These compounds are studied for their role in estrogen metabolism and their influence on how estrogens are processed in the body. Scientific literature describes how DIM may be involved in modulating estrogen pathways, which explains why these compounds are often used in formulas for women during hormonal transitions such as menopause (Zeligs, 1998).
Curcumin, the active compound in Curcuma longa, has been extensively studied in relation to joint comfort and mobility. Clinical studies show that curcumin can help support physical function and comfort with consistent use, especially in adults with increased joint sensitivity (Daily et al., 2016). For this reason, curcumin is often used as a botanical support for maintaining long-term joint flexibility.
During menopause, hormonal changes and physical demands often occur together. Formulas that support both the musculoskeletal system and hormonal metabolism better meet the needs of this life stage. By combining botanical ingredients for joint comfort with compounds studied for their role in estrogen metabolism, this formula was developed to support the body during the hormonal transition characteristic of menopause (Yoon et al., 2018; Zeligs, 1998).
Curcumin naturally has low bioavailability. The addition of piperine, an active compound from black pepper (Piper nigrum), significantly increases curcumin absorption. Clinical research shows that piperine can enhance curcumin’s bioavailability by up to 2000%, allowing the active compounds to be used more efficiently by the body with daily intake (Shoba et al., 1998).
High-dose formulations
Flexible joints during menopause
The OESTRAEDIM™ blend contains high-dose curcumin (95%), traditionally used to support joint flexibility. During menopause, hormonal changes can affect cartilage and movement comfort. This formula provides targeted support to help you stay active and mobile.
Botanical support for female well-being
Broccoli extract provides natural bioactive compounds such as DIM and sulforaphane, which are being studied for their role in estrogen metabolism. OESTRAEDIM™ was developed with attention to the hormonal changes typical of menopause and supports the body during this transition.
Optimised absorption for daily use
Curcumin naturally has low bioavailability. That is why piperine (black pepper) was added, as it has been shown to significantly enhance the absorption of curcumin. This makes the formula suitable for consistent, daily support during menopause.
Greater effectiveness starts with a clean liver
Combine Meno Comfort with the 1-2-3 routine.
Meno Comfort works best when your body can absorb it optimally.
Combine Meno Comfort with steps 1 and 2 for optimal absorption and maximum effectiveness.
Traceable ingredients
FAQS
Questions?
We’re here to help.
At Insentials, pricing reflects the true cost of doing things properly — not cutting corners.
1. Scientifically formulated, not trend-driven
Our formulas are developed based on scientific research, with carefully selected active ingredients used at effective dosages — not underdosed for marketing claims.
2. High-quality, traceable ingredients
We source premium raw materials from trusted suppliers, prioritizing purity, bioavailability, and traceability. Quality ingredients simply cost more — and they perform better.
3. No unnecessary fillers
We focus on what works. No cheap additives, no artificial shortcuts — only ingredients that serve a real functional purpose.
4. Strict European manufacturing standards
Our products are manufactured under rigorous quality controls, ensuring safety, stability, and consistency in every batch.
5. Long-term effectiveness over short-term marketing
We invest more in formulation and quality than in flashy discounts. Our goal is sustainable results, not temporary hype.
In short, you’re not paying for trends — you’re investing in transparency, science, and real efficacy.
At Insentials, we follow a liver-first philosophy. Scientific research shows that a healthy liver is the foundation for better nutrient absorption and long-term effectiveness. Our formulas are clean label, science-backed, and designed to support you day after day.
Yes. Many of our products are designed to complement each other. Our packs and routines help guide you, or you can ask for personalized advice.
Supplements work in a supportive way and their effects are personal. We recommend using the products consistently for at least 3 months to properly evaluate their role in your routine.
Yes. We work with traceable ingredients, evidence-based dosages, and select extracts based on scientific literature and quality standards.
Health starts with the cause
From this vision, nutritional scientist Amandine De Paepe developed Insentials, with a preventive focus on liver health.
AMANDINE DE PAEPE
CEO, Founder Insentials, Food scientist, Orthomolecular nutritionist
CELINE DE GROOTE
Customer Care & Dietitian
Orthomolecular nutrition expert
NELE TIMMERMAN
Science Department & Dietitian
Orthomolecular nutrition expert
JONA DE BAERDEMAEKER
Scientific research team & Dietitian
We stand by our science
WE DON'T SELL MIRACLES
Supplements take time. Our team will guide you with clear expectations and advice. Contact us after your purchase.
FREE SHIPPING FROM €45 (BE)
Worldwide shipping. Orders within the EU are shipped within 1–2 business days.
FLEXIBLE SUBSCRIPTION
You can easily adjust or pause your delivery. Cancellation is possible from month 2.
TALK TO OUR EXPERTS
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"My mission is to address health at its root, with a preventive focus on liver health."
— Amandine de Paepe, Founder of Insentials