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In this episode of our podcast, Debby – Head of Innovation at Insentials – sits down with Dr. Cambré, an expert in aesthetic and regenerative medicine.
They cover everything related to skincare and anti-aging: from Botox and collagen supplementation to cutting-edge technologies like salmon sperm injections and exosomes. Lifestyle, sleep, and stress reduction are also key topics of the conversation.
A discussion full of insights and practical tips for anyone looking to age in a healthy and radiant way.
Dr. Chris Cambré is an aesthetic physician with a background in vascular surgery, trained in Germany.
During his medical training, he developed a passion for the world of aesthetics.
Today, he combines his medical expertise with a strong focus on regenerative medicine, helping people age healthily and vibrantly in a natural way.
In his practice, he works with innovative techniques and treatments that support both appearance and inner health, from supplements and lifestyle coaching to high-end aesthetic procedures.
Dr. Cambré explains what regenerative medicine is really about: it focuses on supporting the body’s natural ability to repair itself, with the goal of aging in a healthy and vibrant way.
Think of treatments using the body’s own substances, such as platelets or plasma, but also supplements, nutritious food, and a conscious lifestyle.
According to Dr. Cambré, you can use as much botox or filler as you like — if your inner health is lacking, it will eventually show on the outside.
“Beauty starts from within,” he emphasizes. That’s why regenerative medicine always goes hand in hand with healthy choices in nutrition, exercise, sleep, and stress management.
Debby shares that she started using Botox in her early thirties and sometimes wonders what it might do to her face in the long run.
“I admit it, I’m a little afraid of what it will look like in twenty years,” she says openly.
Dr. Cambré understands the concern but offers reassurance. According to him, everything comes down to the right dosage and respecting the natural activity of the muscles.
“The dose makes the difference,” he explains. In his clinic, patients are deliberately not scheduled for fixed three-month Botox appointments.
Treating too frequently can cause muscle atrophy, a phenomenon where muscles weaken or even disappear, which leads to the characteristic “frozen Botox face.”
He recommends always allowing the Botox to fully wear off before the next session so that the muscles maintain their movement.
This way, the face ages gradually and naturally. And in the long term? According to Dr. Cambré, you actually look softer and fresher than if you had never used Botox, precisely because the face doesn’t suddenly sag but ages in a controlled, harmonious way.
Debby is curious to know if there are ways to enhance the long-term results of Botox.
Are there supplements or treatments that can support its effect?
According to Dr. Cambré, everything starts with a healthy lifestyle.
“Beauty begins from within. You can use as much Botox and as many fillers as you like, but if your inner health isn’t right, you won’t radiate,” he says.
Supplements play an important role in that process.
He specifically mentions zinc:
“Studies show that zinc supplementation can extend the effect of Botox,” he explains.
By taking zinc daily, the visible results of Botox last longer.
On top of that, zinc also supports the body’s immune system.
For Dr. Cambré, it is therefore an essential supplement in a well-thought-out skincare and anti-aging routine.
Debby shares that she only began taking collagen supplements in her thirties, long before it became a trend.
Back then, she was told that a short, intensive cure could compensate for her deficiencies.
But was that really the right approach?
Dr. Cambré considers collagen to be one of the fundamental pillars of inside-out anti-aging.
“From the age of around 21 to 23, our bodies start losing collagen,” he explains.
Starting supplementation early helps the body compensate for this loss, which has visible effects on the skin, nails, hair, and even the joints, depending on the type of collagen.
Instead of short-term cures, he advises taking a high-quality collagen supplement daily.
“Consistency is key. This way, your body is continuously replenished,” he says.
He also emphasizes that not all forms of collagen are equally well absorbed.
Technology makes a big difference: liquid collagen or collagen with a low molecular weight is often absorbed more efficiently.
And that cheap jar of collagen from the supermarket?
“A waste of money,” says Dr. Cambré firmly. “You’re paying for quality.”
Liquid collagen for optimal absorption
In addition to collagen, Dr. Cambré highlights other supplements that play an important role in slowing skin aging from the inside out.
Omega‑3 fatty acids, for example. They are essential for overall health but, according to him, also contribute to a more youthful appearance.
“I recommend them to almost everyone,” he says.
NADH is another topic that comes up. This compound is gaining more attention on social media, especially on TikTok.
Debby wonders whether NADH is best taken through injections or supplements.
Dr. Cambré acknowledges that injections can be more potent, but oral supplementation is also effective, provided that the right technology is used.
Why is NADH so interesting?
“It works at the cellular level,” he explains.
“It helps preserve the telomeres in your cells.”
Telomeres are the protective caps at the ends of your DNA strands and determine how many times a cell can divide.
With every division, they get shorter; a process linked to aging.
NADH helps slow this process and also supports the mitochondria, the energy factories of our cells.
In other words: healthier cells that last longer.
For Dr. Cambré, NADH is a valuable addition to a routine focused on long-term results; not just for the skin, but also for overall vitality.
Inner Beauty powered by NADH & zinc
Debby curiously asks about a striking new trend: salmon sperm injections.
It may sound unusual, but according to Dr. Cambré, it’s currently one of the most talked-about innovations in aesthetic medicine, and for good reason.
Salmon sperm contains polynucleotides, the building blocks of DNA, which trigger a regenerative process.
“You’re essentially giving genetic material to the skin, helping cells renew themselves more efficiently,” he explains.
These polynucleotides activate a whole cascade of repair mechanisms in the body.
The treatment is mostly intended for the long term: you won’t see results after a single session, but repeated treatments can deliver visible effects.
“The healthier your lifestyle, the better these treatments work,” says Dr. Cambré.
He notices the most impressive results in younger patients. In older skin, the effects are more limited, but combined with collagen and NADH supplementation, it can still make a difference.
In short: not a miracle cure, but certainly a promising addition to the anti-aging arsenal.
The vampire lift is another popular trend Dr. Cambré discusses.
He explains that the technique is based on using your own blood.
During the treatment, blood is drawn and then processed to extract the platelets.
These platelets contain growth factors; natural signaling molecules that stimulate the body to repair and renew itself.
“Your body basically gets a signal: regenerate and rejuvenate here,” says Dr. Cambré.
The process is slow but profound, and just like salmon sperm treatments, repetition is key for lasting results.
“There are no miracle solutions,” he emphasizes.
But if you combine it with a healthy lifestyle and supplements such as collagen and NADH, the effect of these treatments is significantly enhanced.
The vampire lift perfectly fits within the broader concept of regenerative medicine: stimulating the body to renew itself naturally and safely.
Debby asks Dr. Cambré what we can expect in the near future when it comes to anti‑aging.
His answer: exosomes.
Exosomes are tiny particles that cells use to communicate with each other.
They can transfer information, such as DNA and proteins, and thus play a crucial role in regeneration and repair.
“Cells can’t talk like we do,” Dr. Cambré explains. “But through exosomes, they can send each other messages.”
Then comes the key point:
“These exosomes are also packed with growth factors.”
It is precisely these growth factors that can trigger a regenerative effect in the body.
Today, exosomes can already be isolated, but there are currently no human exosomes available on the market for injections.
Plant‑based exosomes do exist, but Dr. Cambré is cautious about them.
“The split between animals and plants dates back millions of years. It’s uncertain whether plant proteins really have any effect in humans,” he says.
What if you’re 40 today and want to still radiate like you’re 30 when you’re 60?
Debby asks the question, and Dr. Cambré is clear: it all starts with your lifestyle.
Nutrition is the first pillar: eat regularly and never overeat.
But just as important is exercise, and in particular, strength training.
“Today we know: it’s all about muscle mass,” says Dr. Cambré.
According to him, muscle mass is the key to aging healthily and staying vital.
He cites the example of a woman who started strength training at 63 and looked younger ten years later than when she began.
Training two to three times per week is ideal, but it must be intense.
“No pain, no gain,” he says.
Debby relates: she used to run a lot, but since switching to strength training, she has seen much better results.
Sleep and stress are also crucial factors.
People who sleep eight hours a night tend to look younger than those who only sleep four or five.
That’s because most of the body’s repair processes happen during sleep.
Poor sleep? Dr. Cambré recommends sleep supplements rather than medication:
“There is no sleeping pill that isn’t addictive.”
And then there’s stress.
“Stress can feed tumors, it makes you crave sugar… Stress is really harmful,” he warns.
Relaxation is therefore essential — but it looks different for everyone.
Walking in nature, exercising, reading, or simply letting go for a while.
The key is to clear your mind at least once a week.
“We are increasingly breathing through our mouths,” says Dr. Cambré. “You can even see it in children.”
According to him, this is linked to the way we eat today: lots of processed foods, which require very little actual chewing.
Less chewing means the muscles in the face and tongue are less active, directly affecting our breathing and even the development of the face.
Interestingly, Dr. Cambré refers to Charles Darwin. He was one of the first to observe that mouth breathing appeared among the bourgeoisie, the wealthier classes who had access to processed foods.
Darwin noticed that jaws were receding, chins were becoming shorter, and children were increasingly breathing with open mouths.
“In poorer populations, this did not happen at the time,” says Dr. Cambré.
“Today, everyone has access to processed foods, and now we see these effects everywhere.”
“When you sleep with your mouth open, you develop gum inflammation. You inhale unfiltered air. And when you enter deep sleep and your muscles relax, your tongue falls back,” explains Dr. Cambré. This blocks proper, deep breathing.
People who sleep with their mouths open snore more, sleep more lightly, and wake up less refreshed.
That’s why he recommends mouth taping; gently taping the lips so the body is forced to breathe through the nose.
“You’ll wake up truly rested. Just try it,” he tells Debby. He speaks from personal experience; he himself used to be a mouth breather.
Correct tongue posture is also crucial. By actively pressing the tongue against the palate, you not only improve breathing but also influence facial structure.
The tongue guides the teeth into the correct position and supports healthy jaw development.
“If we taught children early on to breathe through the nose and position their tongue properly, 90% of jaw surgeries and braces would be unnecessary,” says Dr. Cambré.
He even points to twin studies where the difference between a nasal breather and a mouth breather is clearly visible.
“A nasal breather is always more attractive,” he says with a smile.
And he ends on a reassuring note: “You can definitely train yourself to do this, even later in life.”
Although Dr. Cambré strongly promotes a healthy diet, he emphasizes that nutrition alone is no longer sufficient today.
Debby shares that she eats healthily and consumes a lot of vegetables, but she admits that she is sometimes too lazy to wash them thoroughly. She wonders if that’s a problem.
Dr. Cambré confirms that it is not harmless.
“Large-scale farms spray a lot. Vegetables need to look perfect, so they are heavily treated with pesticides,” he explains.
Even organic vegetables are not completely spared.
And today, there is another invisible threat: PFAS, chemical substances that end up in our environment and in our food.
“Pollution comes from all directions,” he says. “Even in the soil.”
This is why, according to Dr. Cambré, it is essential to always wash vegetables thoroughly, even organic ones.
But even then, he insists, there is still a reason to supplement:
“We know that our vegetables no longer have the same nutritional value as before.
They are mass-produced on depleted soils.”
Soils contain fewer minerals, which has a direct effect on the nutrients we get from our diet.
Debby nods, realizing that more and more people are becoming aware of this.
And this is exactly where supplements provide a valuable addition to a healthy lifestyle:
as a protective buffer against the things we can’t always control.
Botox – “A classic, if used correctly.” → 9/10
Fillers (to restore volume) – “I’m not a big filler fan.” → 7/10
Collagen supplementation – “A basic supplement nowadays.” → 10/10
Powder or shots? – “Depends on the technology, but… shot.” → Shot form
Microneedling – “Very effective if done regularly.” → 8/10
Cold showers → 9/10
Retinol creams – “If it’s the right one.” → 8/10
Profhilo – “Doesn’t work for everyone.” → 6.5/10
At‑home LED therapy – “Better than nothing, but avoid cheap Chinese masks.” → Depends on quality
Non‑surgical facelift (radiofrequency or ultrasound) – “Good as prep, but no miracle.” → 6/10
Deep plane facelift – “If truly needed, the best option.” → 7 to 10/10 depending on indication
Salmon sperm injections – “A bit overhyped, but effective in younger people.” → 6.5/10
Snail mucus serum → 4/10 – overrated
Sugar‑free lifestyle for skin → 10/10 (with a guilty smile: “I cheat sometimes too.”)
Mouth taping → 10/10 – “Everyone should actually do this.”
Castor oil packs → 2/10
Lemon bottle injections – “Not approved, no studies.” → 0/10
HIFU (ultrasound lifting) – “With high‑quality devices like Ulthera: 9/10. Cheap Chinese devices: 3/10.” → Strongly quality‑dependent