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Sponsored article · Metabolism & body shape

Why the weight won't come off, even when you eat less.

7 in 10 women aged 35 to 50 can no longer lose weight. The culprit is invisible: the blood sugar curve, and the hormone that regulates it, GLP-1. GLH-2, by Amandine De Paepe, winner of the ELLE Beauty Awards 2026.

CD
By Claire Delmas
May 5, 2026 · 3 min read
Woman aged 35-50, natural light, calm after a meal
After 35, the way the body handles sugar changes. And with it, what it stores or uses.

After 35, the body stops playing by the usual rules. You eat much as you did before, you move as much as before, and the weight still settles in. It isn't discipline that explains this, it's metabolism: the way your body handles blood sugar.

The invisible spiral.

Every time you eat carbs (bread, pasta, rice, but also a dish that looks perfectly healthy: poke bowl, salmon wrap, granola), blood sugar climbs. Insulin is released to bring it back down. What isn't burned right away is stored as fat.

Two to four hours later, blood sugar crashes. Too fast.

The brain panics:

The brain's message

No fuel left. Quick, fast sugar.

"Eat sugar.
Now."

You snack, the cycle starts again, and that's the weight that quietly settles in over ten years, especially around the belly and hips.

Three options. None is enough on its own.

1. Diets and exercise. Diets work for a while, but they starve the body, which lowers its base metabolic rate : the lost weight comes back, plus a few extra — the yo-yo effect, documented since the 90s. Exercise, essential as it is, doesn't change the way insulin drives storage: you can run three times a week and still gain belly fat.

2. Prescription GLP-1 injections. Since 2023, these weight-loss injections have taken over women's magazines and nutritionists' clinics. They all work with the same molecule: GLP-1, the satiety hormone that slows digestion and steadies blood sugar. The injection is a synthetic copy of a hormone your body already makes.

  • Price: €200 to €400 per month.
  • Frequent side effects: nausea, constipation, digestive fatigue, loss of muscle mass.
  • Dependence: when you stop, the weight comes back in most cases.

What if, instead of injecting GLP-1, we taught the body to make its own?

That's the question Amandine De Paepe, Belgian food scientist, orthomolecular nutritionist and founder of Insentials, spent ten years researching.

Rather than replacing the hormone with a synthetic molecule, her team went the opposite way: isolating a combination of plant actives capable of waking up the body's natural GLP-1 production, and slowing the absorption of carbs upstream.

The patent is called Glucoreductase™. It works in two places:

  1. In the gut, by slowing the absorption of carbs by up to 40%*. The blood sugar curve smooths out, the insulin spike is dampened, the body stores less.
  2. In the digestive system, by stimulating natural GLP-1 production by up to 65%*. Satiety lasts longer, with no injection.

The supplement is called GLH-2. One capsule before your main meal. Awarded by the ELLE International Beauty Awards 2026jury. Used by more than 50,000 women across Belgium, France and the Netherlands, alongside a balanced lifestyle and regular physical activity.

* Methodology note: internal study, N=60 participants, measured by CGM. Details on request.

Françoise
★★★★★5,0 / 5
I've been taking it for almost 3 months and I feel great. The improvement is real, but it takes a bit of patience — the effects really kick in after a few weeks. I recommend it.
✓VerifiedGhent, BE

So what does this mean for you?

No injection No prescription
The timeline of effects
1
From the first week
First feelings of satiety
2
3 to 6 weeks
Sugar cravings settle
3
2 to 3 months
Blood sugar normalises

No capsule makes you lose weight on its own. GLH-2 dampens the insulin spike that pushes the body to store, as part of a balanced diet and regular physical activity. Results vary from person to person.

Discover the Insentials solution
50 000
Women using it
4,49/ 5
Across 116 verified reviews
10yrs
Research & development
ELLE2026
Beauty Awards Winner
GLP-1 Booster
GLH-2 Glucoreductase, pouch
GLH-2 packshot
GLH-2 fact sheet
GLH-2 detail
GLH-2 USP 4
GLH-2 infographic
GLH-2 infographic
GLH-2 timeline
GLH-2 jar
Satiety that lasts  up to 6 hours  after a carb-rich meal

GLH-2

GLUCOREDUCTASE™

Take back control of blood sugar. And of the weight settling in.

4.49 116 reviews
Fewer cravings and sugar urges
Supports steady blood sugar between meals
Optimised metabolic regulation
A GLP-1 injection costs €200 to €400 per month, on prescription. GLH-2 costs €2.10 per day, no prescription, no injection.
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GLH-2 Glucoreductase — 3 pouches
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GLH-2 for 3 months
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Your regular use is rewarded
Amandine De Paepe
The founder

"I wasn't looking to make people lose weight fast. I was looking to understand why the body stores, despite the effort. Ten years later, GLH-2 is the answer."

Amandine De Paepe
Biomedical scientist · Nutrition expert
10 yearsof research
50 000customers
ELLE 2026Winner
Amandine answers on video

The questions you ask us
the most.

How does GLH-2 work?
When should I take GLH-2?
The Science behind GLH-2
Clinical evidence

GLH-2's effect on the blood sugar curve: what changes for your silhouette.

Ten published studies. References available on request.

seuil insuline GLYCÉMIE SANS GLH-2 pic d'insuline → stockage AVEC GLH-2 pic amorti → pas de stockage 0 20 40 60 80 100 Minutes après le repas

Postprandial blood sugar curve · GLH-2 vs placebo.
Lower peak, gentler descent, storage dampened.

+65%
GLP-1 production
Satiety that holds until your next meal.
−40%
Carbohydrate absorption
Fewer peaks, fewer crashes.
6h
Lasting satiety
No more 5pm hunger pang.

Methodology note: internal study, N=60 participants, measured by CGM (continuous glucose monitor). Full methodology available on request.

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Frequently asked questions

What we get asked
the most.

How long until I see results?

The first feelings of satiety appear within the first week. Cravings settle in 3 to 6 weeks. Blood sugar normalises over 2 to 3 months.

Will I lose weight with GLH-2?

GLH-2 contributes to normal carbohydrate metabolism. As part of a balanced diet and regular physical activity, it helps dampen the insulin spike that pushes the body to store. No capsule makes you lose weight alone.

How is it different from a prescription GLP-1 injection?

Prescription GLP-1 injections use a synthetic copy of the hormone. GLH-2 stimulates your own natural GLP-1 production, and slows carbohydrate absorption upstream. No prescription, no injection.

Who is Insentials?

Insentials works according to a liver-first philosophy. Our formulas are clean label, science-based, and designed to support you day after day.

Compatible with my medication?

GLH-2 is compatible with most treatments. If you take an antidiabetic medication, consult your doctor.

Why this price?

Our prices reflect the true cost of work done right: science-based formulas, premium traceable ingredients, no superfluous additives, strict European manufacturing standards.

Can I cancel any time?

Yes, in one click, no questions, no penalty.

Verified Trustpilot reviews.

4,49 / 5 of our customers recommend GLH-2.

Read all reviews
SOPHIE
★★★★★5,0 / 5
"I was very skeptical, but I still wanted to try it, and yes — I don't crave anymore. That craving for sugar/sweets has completely disappeared! I'm delighted! I'll keep going."
✓VerifiedWortegem, BE
LEEN
★★★★★5,0 / 5
"With GLH-2 and better food choices, I lost 6 kg in 45 days. I crave sweets much less and I feel full faster."
✓VerifiedAntwerp, BE
HILDE B.
★★★★★5,0 / 5
"I've been taking it for almost 3 months and I feel great. The improvement is real, but it takes a bit of patience — the effects really kick in after a few weeks. I recommend it."
✓VerifiedGhent, BE
KARIMA
★★★★★5,0 / 5
"Clean, honest, natural products. My cravings have dropped, I feel better and my blood sugar is more stable too. Love it!"
✓VerifiedGhent, BE
KARIMA
★★★★★5,0 / 5
"I took GLH-2 for 1 month combined with exercise 2 to 3 times a week and I dropped a clothing size! Highly recommended."
✓VerifiedBrussels, BE
I. W.
★★★★☆4,0 / 5
"Since I've been taking GLH-2, no more cravings for sweets and my hunger has disappeared. My weight stays stable even on vacation. Recommended!"
✓VerifiedBelgium
HILDE
★★★★★5,0 / 5
"Loyal GLH-2 fan. Real, noticeable difference and lovely gut comfort day-to-day."
✓VerifiedBelgium
ANONYMOUS
★★★★★5,0 / 5
« Loyal fan of GLH-2. Really noticeable difference and very pleasant gut comfort on a daily basis. »
✓VerifiedBrussels, BE
IMRE
★★★★★5,0 / 5
"Fantastic product for the gut and blood sugar. Pricey, yes, but it's worth it."
✓VerifiedAntwerp, BE
Beyond the scales

Blood sugar.
It shows up on the outside too.

Fewer spikes isn't just a concept. It's what our customers notice first, even before the silhouette.

01
The gut

Not all carbohydrates are broken down immediately. Some reach the colon, where they nourish beneficial gut bacteria supporting satiety and metabolic balance.

02
The gut

Not all carbohydrates are digested immediately. Some reach the colon, where they feed beneficial gut bacteria that support satiety and metabolic balance.

03
The energy

The 3pm slump, the 6pm mood dip: those are blood sugar crashes in disguise. When the curve smooths out, your energy holds.

Break the cycle

Stopping fat storage isn't about discipline. It's about biology.

You don't break out of the cycle by gritting your teeth. You break out when the body no longer has reasons to store.

Try it for 30 days
Free shipping · 4.49/5 from 116 reviews
Subscription €63/month · €2.10/day
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Insentials
Wellness · Metabolism & body shape
Discover GLH-2